D'Amico, Francesco, Rehill, Amritpal ORCID: 0000-0003-3826-2711, Knapp, Martin ORCID: 0000-0003-1427-0215, Aguirre, Elisa, Donovan, Helen, Hoare, Zoë, Hoe, Juanita, Russell, Ian, Spector, Aimee, Streater, Amy, Whitaker, Christopher, Woods, Robert T and Orrell, Martin (2015) Maintenance cognitive stimulation therapy: an economic evaluation within a randomised controlled trial. Journal of the American Medical Directors Association, 16 (1). pp. 63-70. ISSN 1525-8610
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Abstract
Background Cognitive Stimulation Therapy (CST) is effective and cost-effective for people with mild-to-moderate dementia when delivered bi-weekly over seven weeks. Aims To examine whether longer-term (maintenance) CST is cost-effective when added to usual care. Methods Cost-effectiveness analysis within multicentre, single-blind, pragmatic randomised controlled trial; subgroup analysis for people taking acetylcholinesterase inhibitors (ACHEIs). 236 participants with mild-to-moderate dementia received CST for seven weeks. They were randomised to either weekly maintenance CST added to usual care or usual care alone for 24 weeks. Results Although outcome gains were modest over 6 months, maintenance CST appeared cost-effective when looking at self-rated quality of life as primary outcome, and cognition (MMSE) and proxy-rated quality-adjusted life years as secondary outcomes. CST in combination with ACHEIs offered cost-effectiveness gains when outcome was measured as cognition. Conclusions Continuation of CST is likely to be cost-effective for people with mild-to-moderate dementia. Trial registration Current controlled trials ISRCTN26286067.
Item Type: | Article |
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Official URL: | http://www.journals.elsevier.com/journal-of-the-am... |
Additional Information: | © 2015 AMDA - The Society for Post-Acute and Long-Term Care Medicine © CC BY 3.0 |
Divisions: | Social Policy Care Policy and Evaluation Centre |
Subjects: | R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine |
Date Deposited: | 09 Dec 2014 09:19 |
Last Modified: | 14 Nov 2024 06:33 |
Projects: | Programme Grants for Applied Research scheme (RP-PG-060-1083) |
Funders: | National Institute for Health Research |
URI: | http://eprints.lse.ac.uk/id/eprint/60460 |
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