McGuire, Alistair 
ORCID: 0000-0002-5367-9841, Davie, P, Hughes, D and McMurray, J
(1997)
Cost-effectiveness of different ACE inhibitor treatment scenarios in post-myocardial infarction.
European Heart Journal, 18 (9).
pp. 1411-1415.
ISSN 0195-668X
Abstract
AIMS: To assess the cost-effectiveness of three different treatment strategies for the use of ACE inhibitors after myocardial infarction. These were (a) a high risk (AIRE type) strategy, (b) an intermediate risk (SAVE type) strategy, and (c) initial, short-term treatment of all patients followed by long-term treatment according to (a) or (b). METHODS AND RESULTS: Incremental costs per life year gained were calculated for each of the above scenarios. The most optimistic cost per life year gained over 10 years, for (a) was £1752 and for (b) was £2962. Strategy (c) increased the cost per life year gained of (a) to £2017 and (b) to £3110. The incremental cost-effectiveness ratio was found to be very sensitive to drug cost. CONCLUSIONS: If a low cost ACE inhibitor is used, initial treatment of relatively unselected patients followed by long-term treatment of those at high and medium risk maximizes benefit at an acceptable cost. Use of an ACE inhibitor after myocardial infarction is very cost-effective by comparison with many other treatments.
| Item Type: | Article |
|---|---|
| Official URL: | http://eurheartj.oxfordjournals.org/ |
| Additional Information: | © 1997 the European Society of Cardiology |
| Divisions: | Social Policy LSE Health |
| Subjects: | R Medicine > R Medicine (General) |
| Date Deposited: | 06 Feb 2009 14:19 |
| Last Modified: | 11 Dec 2024 22:05 |
| URI: | http://eprints.lse.ac.uk/id/eprint/22480 |
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