Hou, Dingchun, Zhao, Yuxing, Liang, Bo, Liu, Chang, Pei, Lijun and Chen, Gong (2025) Association of psychological resilience and its trajectories with frailty in middle-aged and older populations: a prospective cohort study. Journal of Affective Disorders, 389. ISSN 0165-0327
Full text not available from this repository.Abstract
Whether frailty risk is affected by psychological resilience (PR) and its long-term progression remains unclear. We aimed to estimate associations between them in middle-aged and older populations. Prospective cohorts were constructed of adults aged ≥50 years from 2006 to 2022 in the Health and Retirement Study. PR was measured by the simplified resilience score. PR trajectories were modeled by group-based trajectory modeling. Frailty was assessed by the Fried frailty phenotype. Cox proportional hazard models were applied to estimate the associations. 15,110 participants were included (median [interquartile range] age = 63 [56-73] years; 8717 [57.69 %] females). Compared with the Q level of PR, its Q , Q , and Q decreased the risk of frailty by 17 % (hazard ratio [HR] = 0.83, 95 % confidence interval [95%CI]: 0.75-0.91), 32 % (HR = 0.68, 95%CI: 0.61-0.76) and 48 % (HR = 0.52, 95%CI: 0.45-0.58), respectively, with a significant age-PR interaction effect. 4783 participants were included to model trajectories of PR over an eight-year period, identifying three trajectories: low resilience (5.83 %), moderate resilience (33.45 %), and high resilience (60.72 %). Compared with high resilience, moderate resilience and low resilience increased the risk of frailty by 43 % (HR = 1.43, 95 % CI: 1.22-1.68) and 104 % (HR = 2.04, 95 % CI: 1.59-2.63). Higher levels of psychological resilience were associated with a reduced risk of frailty. Middle-aged individuals with lower psychological resilience may be important target populations for frailty prevention and management. Monitoring trajectories of psychological resilience is important for early frailty screening, prognosis assessment, and intervention.
| Item Type: | Article |
|---|---|
| Additional Information: | © 2025 Elsevier B.V. |
| Divisions: | LSE |
| Subjects: | H Social Sciences > HQ The family. Marriage. Woman B Philosophy. Psychology. Religion > BF Psychology |
| Date Deposited: | 23 Jun 2025 15:00 |
| Last Modified: | 23 Jun 2025 18:55 |
| URI: | http://eprints.lse.ac.uk/id/eprint/128534 |
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