Maqsood, Muhammad Haisum, Nguyen, Ryan, Chang, Ryan, Kundi, Harun, Hagan, Kobina, Butt, Sara, Titus, Anoop, Hyder, Adnan A., Javed, Umair, Al-Kindi, Sadeer, Blaha, Michael J., Mossialos, Elias 
ORCID: 0000-0001-8664-9297, Nasir, Khurram and Javed, Zulqarnain
(2024)
Unfavorable social determinants of health and mortality risk by cardiovascular disease status: findings from a National Study of United States Adults.
American Heart Journal, 267.
95 - 100.
ISSN 0002-8703
Abstract
Background: The association between cumulative burden of unfavorable social determinants of health (SDoH) and all-cause mortality has not been assessed by atherosclerotic cardiovascular disease (ASCVD) status on a population level in the United States. Methods: We assessed the association between cumulative social disadvantage and all-cause mortality by ASCVD status in the National Health Interview Survey, linked to the National Death Index. Results: In models adjusted for established clinical risk factors, individuals experiencing the highest level of social disadvantage (SDoH-Q4) had over 1.5 (aHR = 1.55; 95%CI = 1.22, 1.96) and 2-fold (aHR = 2.21; 95% CI = 1.91, 2.56) fold increased risk of mortality relative to those with the most favorable social profile (SDoH-Q1), respectively for adults with and without ASCVD; those experiencing co-occurring ASCVD and high social disadvantage had up to four-fold higher risk of mortality (aHR = 3.81; 95%CI = 3.36, 4.32). Conclusions: These findings emphasize the importance of a healthcare model that prioritizes efforts to identify and address key social and environmental barriers to health and wellbeing, particularly in individuals experiencing the double jeopardy of clinical and social risk.
| Item Type: | Article |
|---|---|
| Official URL: | https://www.sciencedirect.com/journal/american-hea... |
| Additional Information: | © 2023 Elsevier Inc. |
| Divisions: | Health Policy |
| Subjects: | R Medicine > RA Public aspects of medicine |
| Date Deposited: | 04 Jan 2024 16:24 |
| Last Modified: | 10 Nov 2025 19:39 |
| URI: | http://eprints.lse.ac.uk/id/eprint/121170 |
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