Cookies?
Library Header Image
LSE Research Online LSE Library Services

The economic cost of treatment-resistant depression in patients referred to a specialist service

McCrone, Paul, Rost, Felicitas, Koeser, Leonardo, Koutoufa, Iakovina, Stephanou, Stephanie, Knapp, Martin, Goldberg, David, Taylor, David and Fonagy, Peter (2017) The economic cost of treatment-resistant depression in patients referred to a specialist service. Journal of Mental Health. ISSN 0963-8237

[img]
Preview
Text - Accepted Version
Download (422kB) | Preview
Identification Number: 10.1080/09638237.2017.1417562

Abstract

Background: Patients with treatment-resistant depression (TRD) suffer very significant morbidity and are at a disadvantage concerning optimal clinical management. There are high associated societal costs. Aims: A detailed analysis of health economic costs in the United Kingdom in a group manifesting a severe form of TRD in the 12 months before their participation in a major randomized controlled treatment trial. Methods: The sample consisted of 118 participants from the Tavistock Adult Depression Study. Recruitment was from primary care on the basis of current major depression disorder of at least 2 years’ duration and two failed treatment attempts. Service utilization was assessed based on self-report and general practitioner (GP) medical records. Generalized linear models were used to identify predictors of cost. Results: All participants used GP services. Use of other doctors and practice nurses was also high. The mean total societal cost was £22 124, 80% of which was due to lost work and care required of families. Level of general functioning was found to be the most consistent predictor of costs. Conclusions: Severe forms of TRD are associated with high costs in which unpaid care and lost work predominate. Treatments that improve functioning may reduce the large degree of burden.

Item Type: Article
Official URL: http://www.tandfonline.com/toc/ijmh20/current
Additional Information: © 2017 Informa UK Limited
Divisions: Health Policy
Subjects: H Social Sciences > HN Social history and conditions. Social problems. Social reform
R Medicine > RA Public aspects of medicine
Sets: Departments > Health Policy
Date Deposited: 22 Feb 2018 14:50
Last Modified: 20 Nov 2019 12:19
URI: http://eprints.lse.ac.uk/id/eprint/86834

Actions (login required)

View Item View Item

Downloads

Downloads per month over past year

View more statistics