Auvert, Bertran, Ballard, Ron, Campbell, Catherine, Carael, Michel, Carton, Matthieu, Fehler, Glenda, Gouws, Eleanor, MacPhail, Catherine, Taljaard, Dirk, Van Dam, Johannes and Williams, Brian (2001) HIV infection among youth in a South African mining town is associated with herpes simplex virus-2 seropositivity and sexual behaviour. AIDS, 15 (7). pp. 885-896. ISSN 0269-9370
Full text not available from this repository.Abstract
Objectives: To determine the seroprevalence of HIV and herpes simplex virus-2 (HSV-2) by age and gender among young people aged 14-24 years in a South African town and to identify risk factors for HIV infection. Design: A community-based, cross-sectional study was conducted on a random sample of men (n = 723) and women (n = 784) living in a township in the Carletonville district of South Africa. Methods: Potential demographic and behavioural risk factors associated with HIV were recorded by questionnaire and biological tests were performed on serum and urine. Data analysis was performed using multivariate logistic regression. Results: Among men and women the prevalence of HIV infection was 9.4 and 34.4%, respectively, and of positive HSV-2 serology was 17.0 and 53.3%, respectively. Among 24-year-old women the prevalence of HIV was 66.7% [95% confidence interval (CI), 54.6-77.3%]. HSV-2 seropositivity was a strong independent risk factor for HIV infection with odds ratios of 5.3 (95% CI, 2.7-10.3) for men and 8.4 (95% CI, 4.9-14.2) for women. There was no independent effect of age at first sex or serological markers of other sexually transmitted infections on HIV infection. Conclusions: HIV infection among young women increases rapidly after the onset of sexual activity and reaches extremely high levels by 24 years of age. These findings suggest that rates of HIV transmission from men to women are high and that HSV-2 plays a major role in the spread of HIV in this population.
| Item Type: | Article |
|---|---|
| Official URL: | http://journals.lww.com/aidsonline/pages/default.a... |
| Additional Information: | © 2001 Lippincott Williams & Wilkins |
| Divisions: | Psychological and Behavioural Science |
| Subjects: | R Medicine > RA Public aspects of medicine |
| Date Deposited: | 04 Nov 2008 11:28 |
| Last Modified: | 11 Dec 2024 22:26 |
| URI: | http://eprints.lse.ac.uk/id/eprint/7603 |
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