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A comparative study of drug listing recommendations and the decision-making process in Australia, the Netherlands, Sweden, and the UK

Salas-Vega, Sebastian, Bertling, Annika and Mossialos, Elias (2016) A comparative study of drug listing recommendations and the decision-making process in Australia, the Netherlands, Sweden, and the UK. Health Policy, 120 (10). pp. 1104-1114. ISSN 0168-8510

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Identification Number: 10.1016/j.healthpol.2016.08.006

Abstract

Drug listing recommendations from health technology assessment (HTA) agencies often fail to coincide with one another. We conducted a comparative analysis of listing recommendations in Australia (PBAC), the Netherlands (CVZ), Sweden (TLV) and the UK (NICE) over time, examined interagency agreement, and explored how process-related factors—including time delay between HTA evaluations, therapeutic indication and orphan drug status, measure of health economic value, and comparator—impacted decision-making in drug coverage. Agreement was poor to moderate across HTA agency listing recommendations, yet it increased as the delay between HTA agency appraisals decreased, when orphan drugs were assessed, and when low-value medicines (immunosuppressants, antineoplastics) were removed from the sample. International differences in drug listing recommendations seem to occur in part due to inconsistencies in how the supporting evidence informs assessment, but also to differences in how domestic priorities shape the value-based decision-making process.

Item Type: Article
Official URL: https://www.journals.elsevier.com/health-policy/
Additional Information: © 2016 Elsevier Ireland Ltd.
Divisions: Social Policy
Subjects: R Medicine > RA Public aspects of medicine
R Medicine > RS Pharmacy and materia medica
Sets: Departments > Social Policy
Research centres and groups > LSE Health and Social Care
Date Deposited: 05 Apr 2017 12:31
Last Modified: 20 Apr 2019 01:36
URI: http://eprints.lse.ac.uk/id/eprint/72487

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