Naci, Huseyin ORCID: 0000-0002-7192-5751
(2016)
Communication of treatment rankings obtained from network meta-analysis using data visualization.
Circulation: Cardiovascular Quality and Outcomes, 9 (5).
pp. 605-608.
ISSN 1941-7705
Abstract
The number of published network meta-analysis (NMA) reports has increased substantially in recent years. NMAs combine direct and indirect evidence and enable comparisons between all relevant treatment options for a given disease, even when some treatments have not been directly compared with each other. In the absence of randomized trials comparing all treatment options to each other, NMAs address important information needs of patients and clinicians about the comparative effectiveness of treatment alternatives. NMA results may be difficult to communicate and interpret effectively given the large volume of complex information generated on multiple alternative treatments with multiple benefit and harm outcomes. For example, NMA comparing 5 treatments result in 10 pair-wise comparisons; if results are available for 3 benefit and 3 harm outcomes, decision makers are faced with 60 sets of results. Identifying the best treatment option to initiate therapy is, thus, not straightforward. Although several graphical and tabular displays exist to report the pertinent results of NMAs, existing reporting guidelines differ in their recommendations. Consequently, there is significant variation in the current way NMA findings are reported and presented...
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