Cost-effectiveness of exercise as a therapy for behavioural and psychological symptoms of dementia within the EVIDEM-E randomised controlled trial

D'Amico, Francesco, Rehill, Amritpal ORCID: 0000-0003-3826-2711, Knapp, Martin ORCID: 0000-0003-1427-0215, Lowery, David, Cerga-Pashoja, Arlinda, Griffin, Mark, Iliffe, Steve and Warner, James (2016) Cost-effectiveness of exercise as a therapy for behavioural and psychological symptoms of dementia within the EVIDEM-E randomised controlled trial. International Journal of Geriatric Psychiatry, 31 (6). pp. 656-665. ISSN 0885-6230

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Abstract

Objective Although available evidence is modest, exercise could be beneficial in reducing behavioural and psychological symptoms of dementia. We aim to evaluate the cost-effectiveness of a dyadic exercise regimen for individuals with dementia and their main carer as therapy for behavioural and psychological symptoms of dementia. Methods Cost-effectiveness analysis within a two-arm, pragmatic, randomised, controlled, single-blind, parallel-group trial of a dyadic exercise regimen (individually tailored, for 20–30 min at least five times per week). The study randomised 131 community-dwelling individuals with dementia and clinically significant behavioural and psychological symptoms with a carer willing and able to participate in the exercise regimen; 52 dyads provided sufficient cost data for analyses. Results Mean intervention cost was £284 per dyad. For the subsample of 52 dyads, the intervention group had significantly higher mean cost from a societal perspective (mean difference £2728.60, p = 0.05), but costs were not significantly different from a health and social care perspective. The exercise intervention was more cost-effective than treatment as usual from both societal and health and social care perspectives for the measure of behavioural and psychological symptoms (Neuropsychiatric Inventory). It does not appear cost-effective in terms of cost per quality-adjusted life year gain. Conclusions The exercise intervention has the potential to be seen as cost-effective when considering behavioural and psychological symptoms but did not appear cost-effective when considering quality-adjusted life year gains.

Item Type:	Article
Official URL:	http://onlinelibrary.wiley.com/journal/10.1002/(IS...
Additional Information:	© 2015 John Wiley & Sons, Ltd
Divisions:	Care Policy and Evaluation Centre
Subjects:	H Social Sciences > HV Social pathology. Social and public welfare. Criminology R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine R Medicine > RT Nursing R Medicine > RZ Other systems of medicine
Date Deposited:	10 Dec 2015 17:10
Last Modified:	28 Sep 2025 23:54
Projects:	RP- PG -0606-1005
Funders:	National Institute for Health Research
URI:	http://eprints.lse.ac.uk/id/eprint/64657

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