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Hematological and biochemical data obtained in rural northern Uganda

Palacpac, Nirianne, Ntege, Edward, Balikagala, Betty, Yeka, Adoke, Shirai, Hiroki, Suzuki, Nahoko, Nsereko, Christopher, Kanoi, Bernard, Okada, Takuya, Egwang, Thomas and Horii, Toshihiro (2014) Hematological and biochemical data obtained in rural northern Uganda. International Journal of Environmental Research and Public Health, 11 (5). pp. 4870-4885. ISSN 1661-7827

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Identification Number: 10.3390/ijerph110504870

Abstract

Reference intervals for common hematological and clinical chemistry parameters constitute an important basis for health care. Moreover, with increasing priority in drug and vaccine development for infectious diseases in Africa, the first priority is the safety evaluation and tolerability of the candidate interventions in healthy populations. To accurately assess health status and address adverse events, clinical reference intervals in the target population are necessary. We report on hematological and biochemical indices from healthy volunteers who participated in a clinical trial in Lira, northern Uganda. Median and nonparametric 95% percentiles on five hematology and 15 biochemistry analytes are shown. Although most hematological analytes conformed to reported reference intervals and trends in Africa, literature review from different African countries highlight the need for a region-specific children reference interval that can be appropriate for the population.

Item Type: Article
Official URL: http://www.mdpi.com/journal/ijerph
Additional Information: © 2014 The Authors, licensee MDPI AG (Basel, Switzerland)
Divisions: Social Policy
Subjects: G Geography. Anthropology. Recreation > GF Human ecology. Anthropogeography
H Social Sciences > HV Social pathology. Social and public welfare. Criminology
R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine
R Medicine > RB Pathology
Sets: Departments > Social Policy
Date Deposited: 15 Jul 2014 08:23
Last Modified: 20 Oct 2020 04:22
Projects: Development and Sustainability of Malaria Vaccine Clinical Research Center (38201103-01)
Funders: Research Foundation for Microbial Diseases of Osaka University (BIKEN);, 'Funds for integrated promotion of social system reform and research and development', MEXT
URI: http://eprints.lse.ac.uk/id/eprint/57819

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