Jackson, Timothy L., Nicod, Elena, Angelis, Aris 
ORCID: 0000-0002-0261-4634, Grimaccia, Federico, Prevost, Toby, Simpson, Andrew and Kanavos, Panos ORCID: 0000-0001-9518-3089
(2013)
Vitreous attachment in age-related macular degeneration, diabetic macular edema, and retinal vein occlusion.
Retina, 33 (6).
pp. 1099-1108.
ISSN 1539-2864
Abstract
To determine if there is an association of vitreous attachment and wet age-related macular degeneration (AMD), diabetic macular edema, and retinal vein occlusion. METHODS:: Systematic review and metaanalysis. RESULTS:: Sixteen of 1,025 articles were eligible. In wet AMD, the prevalence of vitreomacular adhesion and posterior vitreous detachment was 23% (654 eyes) and 41% (251), respectively. Vitreomacular adhesion prevalence was 2.15 times that of controls (95% confidence interval, 1.34-3.48; p = 0.002) and 2.54 times that of dry AMD (confidence interval, 0.88-7.36; p 0.09); posterior vitreous detachment prevalence was lower than controls (relative risk 0.77; confidence interval, 0.64-0.93; p = 0.007) and dry AMD (0.56; confidence interval, 0.27-1.14; p = 0.11). It was not possible to determine the prevalence of vitreous attachment in diabetic macular edema, but vitreomacular traction was present in 29% of 188 surgical cases. The prevalence of posterior vitreous detachment in eyes with central and branch retinal vein occlusion was 30% (56 eyes) and 31% (71 eyes), respectively, versus 25% (64 eyes) in controls. CONCLUSION:: Observational studies of sufficient quality indicate that eyes with wet AMD have double the expected prevalence of vitreomacular adhesion and are less likely to have a posterior vitreous detachment. More controlled studies of diabetic macular edema and retinal vein occlusion are needed.
| Item Type: | Article |
|---|---|
| Official URL: | http://journals.lww.com/retinajournal/pages/defaul... |
| Additional Information: | © 2013 Ophthalmic Communications Society, |
| Divisions: | European Institute Social Policy LSE Health |
| Subjects: | R Medicine > R Medicine (General) |
| Date Deposited: | 22 Mar 2013 15:44 |
| Last Modified: | 01 Nov 2024 05:23 |
| URI: | http://eprints.lse.ac.uk/id/eprint/49378 |
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