Skottun, Bernt C. and Skoyles, John R. (2011) Visually evoked potentials, NMDA receptors and the magnocellular system in schizophrenia. Acta neuropsychiatrica, Online . ISSN 0924-2708
Background: It has been claimed that schizophrenia can be linked to the magnocellular system by way of N-methyl-d-aspartate (NMDA) receptors. The present report examines this claim. Methods: A review is made of relevant research literature. Results: The NMDA studies that have been referenced to connect visual deficits in schizophrenia to the magnocellular system are based on the cat, a species whose visual system is fundamentally different from that of primates. The cat visual system cannot easily be divided into magno- and a parvocellular portions. Conclusions: Owing to the substantial differences between the visual systems of cats and primates, it is difficult to link sensory abnormalities in schizophrenia specifically to the magnocellular system based on data from the cat.
|Additional Information:||© 2011 Wiley-Blackwell|
|Uncontrolled Keywords:||ISI, cat, lateral geniculate nucleus, monkey, motion, parvocellular, vision|
|Library of Congress subject classification:||R Medicine > RA Public aspects of medicine|
|Sets:||Research centres and groups > Centre for Philosophy of Natural and Social Science (CPNSS)|
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