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Visually evoked potentials, NMDA receptors and the magnocellular system in schizophrenia

Skottun, Bernt C. and Skoyles, John R. (2011) Visually evoked potentials, NMDA receptors and the magnocellular system in schizophrenia. Acta Neuropsychiatrica, Online. ISSN 0924-2708

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Identification Number: 10.1111/j.1601-5215.2011.00611.x


Background: It has been claimed that schizophrenia can be linked to the magnocellular system by way of N-methyl-d-aspartate (NMDA) receptors. The present report examines this claim. Methods: A review is made of relevant research literature. Results: The NMDA studies that have been referenced to connect visual deficits in schizophrenia to the magnocellular system are based on the cat, a species whose visual system is fundamentally different from that of primates. The cat visual system cannot easily be divided into magno- and a parvocellular portions. Conclusions: Owing to the substantial differences between the visual systems of cats and primates, it is difficult to link sensory abnormalities in schizophrenia specifically to the magnocellular system based on data from the cat.

Item Type: Article
Official URL:
Additional Information: © 2011 Wiley-Blackwell
Divisions: CPNSS
Subjects: R Medicine > RA Public aspects of medicine
Sets: Research centres and groups > Centre for Philosophy of Natural and Social Science (CPNSS)
Date Deposited: 22 Nov 2011 16:25
Last Modified: 20 Feb 2021 04:40

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