Cookies?
Library Header Image
LSE Research Online LSE Library Services

Morbidity indicators of Schistosoma mansoni: relationship between infection and anemia in Ugandan schoolchildren before and after praziquantel and albendazole chemotherapy

Koukounari, Artemis, Fenwick, Alan, Whawell, S., Kabatereine, Narcis B., Kazibwe, Francis, Tukahebwa, Edridah, Stothard, J. Russell, Donnelly, Christl A. and Webster, Joanne P. (2006) Morbidity indicators of Schistosoma mansoni: relationship between infection and anemia in Ugandan schoolchildren before and after praziquantel and albendazole chemotherapy. American Journal of Tropical Medicine and Hygiene, 75 (2). pp. 278-286. ISSN 0002-9637

Full text not available from this repository.

Abstract

The potential relationship between Schistosoma mansoni and anemia was examined using data obtained by the Schistosomiasis Control Initiative (SCI) before (baseline) and 1 year after (follow-up) a chemotherapeutic treatment program in Uganda. Changes in hemoglobin (Hb) levels in 2,788 children in relation to their schistosomiasis and/or hookworm infection intensity category and baseline anemia status were analyzed. At baseline, significant predictors of childhood anemia were intensities of S. mansoni and hookworm infection. At follow-up, moderate or heavy hookworm as well as heavy S. mansoni infections were important. Children heavily infected with S. mansoni or hookworm had significantly lower Hb counts at baseline compared with those not infected. Among anemic children at the baseline survey, a significant increase in Hb counts of 0.834 g/dL after treatment was found. Our results suggest that anemia is associated with schistosomiasis and hookworm in Ugandan children and that such anemia shows a significant improvement after chemotherapy.

Item Type: Article
Official URL: http://www.ajtmh.org/
Additional Information: © 2006 The American Society of Tropical Medicine
Library of Congress subject classification: D History General and Old World > DT Africa
R Medicine > RA Public aspects of medicine
Sets: Departments > Statistics
Rights: http://www.lse.ac.uk/library/usingTheLibrary/academicSupport/OA/depositYourResearch.aspx
Date Deposited: 01 Aug 2011 13:51
URL: http://eprints.lse.ac.uk/37723/

Actions (login required)

Record administration - authorised staff only Record administration - authorised staff only