Library Header Image
LSE Research Online LSE Library Services

Costs of schizophrenia

Knapp, Martin ORCID: 0000-0003-1427-0215 and Razzouk, Denise (2008) Costs of schizophrenia. Psychiatry, 7 (11). pp. 491-494. ISSN 1476-1793

Full text not available from this repository.

Identification Number: 10.1016/j.mppsy.2008.08.008


The economic impact of serious conditions such as schizophrenia is felt widely. The impact on overall health care budgets can be as much as 3% of the total, but there are also other costs, especially those associated with lost productivity, as typically only about one-fifth of all people with schizophrenia are able to find paid work. Decisions about optimal interventions for schizophrenia need to take account of these wide costs alongside the equally wide range of potential outcomes (not just symptom effects, but impacts on personal functioning, social interaction, employment, family relations, and quality of life). Antipsychotics are at the heart of treatment. A fundamental question for those responsible for purchasing medications is whether it is worth paying the inevitably higher prices. Opinion remains divided on this cost-effectiveness question: some studies have concluded that the second-generation antipsychotics are more cost-effective than first-generation medications, but two publicly funded studies (CATIE in the USA and CUtLASS in the UK) have reached the opposite conclusion. Outside the medication field there are fewer economic evaluations of schizophrenia interventions. Cognitive remediation therapy has been shown to produce significant improvements in memory among people with schizophrenia and cognitive deficits. There is also evidence that these improvements were achieved at no additional cost. Regarding service interventions, much attention is now focused on the individual placement and support model, which can improve access to work for people with psychotic illnesses, without any observable corresponding clinical deterioration. Again there is evidence of cost-effectiveness.

Item Type: Article
Official URL:
Additional Information: © 2008 Elsevier
Divisions: Social Policy
Personal Social Services Research Unit
Subjects: R Medicine > RA Public aspects of medicine
Date Deposited: 20 Feb 2011 16:44
Last Modified: 16 May 2024 00:47

Actions (login required)

View Item View Item