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Economic evaluation of the FIBROWALK multicomponent intervention in online and outdoor formats for fibromyalgia (The On&Out Study)

Auer, William, Serrat, Mayte, Sanabria-Mazo, Juan P., Royuela-Colomer, Estíbaliz, Pérez-Aranda, Adrián, Ferrés, Sonia, Robles, Brenda, D’Amico, Francesco, Almirall, Miriam, Cardeñosa, Eugenia, Borràs, Xavier, Luciano, Juan V. and Feliu-Soler, Albert (2025) Economic evaluation of the FIBROWALK multicomponent intervention in online and outdoor formats for fibromyalgia (The On&Out Study). Journal of Pain. ISSN 1526-5900 (In Press)

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Identification Number: 10.1016/j.jpain.2025.105515

Abstract

Fibromyalgia (FM) is a chronic condition with substantial healthcare and societal costs. Although multicomponent interventions are widely available, evidence of their economic impact remains scarce. This study evaluated the cost-utility and cost-effectiveness of the FIBROWALK intervention in online (FIBRO-On) and outdoor (FIBRO-Out) formats, compared to treatment as usual (TAU), for individuals with FM. An economic evaluation (n = 225) was conducted over six months from government (total costs) and healthcare (direct costs) perspectives. The follow-up assessment was conducted six months after baseline, which corresponds to three months after the end of the 12-week intervention. Direct and indirect costs were collected through the Client Service Receipt Inventory. Cost-utility was assessed with Quality Adjusted Life Years (QALYs) and cost-effectiveness with the Revised Fibromyalgia Impact Questionnaire (FIQR). FIBRO-On was superior to TAU in reducing specialized healthcare costs (Cohen’s d = 0.71), improving perceived health (d = 0.50), and reducing FM severity (d = 0.56). Compared to FIBRO-Out, FIBRO-On also reduced healthcare costs and improved both QALYs and FIQR scores. In contrast, FIBRO-Out led to significantly higher costs than TAU and showed no significant benefit in QALYs or FIQR scores. Across intention-to-treat, complete case, and per-protocol analyses, FIBRO-On was also the more favorable intervention, particularly in comparison to FIBRO-Out. These findings suggest that FIBRO-On may be a cost-effective intervention for managing FM compared to TAU or FIBRO-Out. Furthermore, they underscore the potential benefits of exploring digital interventions such as FIBRO-On to improve accessibility and promote efficient use of healthcare resources to manage FM. Trial number NCT05377567 Perspective Economic evaluations of interventions for fibromyalgia are crucial to guide healthcare decisions and optimize resource allocation. This study shows that the multicomponent FIBROWALK intervention in its online format (FIBRO-On) offers good value for money compared to TAU or the outdoor format (FIBRO-Out), based on cost-utility and cost-effectiveness analyses performed from a government and healthcare perspective.

Item Type: Article
Divisions: Care Policy and Evaluation Centre
Subjects: R Medicine > RA Public aspects of medicine
Date Deposited: 08 Sep 2025 11:27
Last Modified: 11 Sep 2025 12:31
URI: http://eprints.lse.ac.uk/id/eprint/129426

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