Perinatal and neonatal factors and mental disorders in children and adolescents: looking for the contributions of the early environment to common and dissociable aspects of psychopathology

Leusin, Fabiane, Damiano, Rodolfo Furlan, Mendes, Lorenna Sena Teixeira, Hoffmann, Maurício Scopel, Manfro, Arthur Gus, Pan, Pedro Mario, Gadelha, Ary, de Jesus Mari, Jair, Manfro, Gisele Gus, Miguel, Eurípedes Constantino, Rohde, Luis Augusto, Bressan, Rodrigo Affonseca and Salum, Giovanni Abrahão (2024) Perinatal and neonatal factors and mental disorders in children and adolescents: looking for the contributions of the early environment to common and dissociable aspects of psychopathology. European Child and Adolescent Psychiatry. ISSN 1018-8827

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Abstract

High rates of co-occurrence of mental disorders have been hypothesized to represent a result of common susceptibility to overall psychopathology. The purpose of this study is to test the hypothesis that commonalities among psychiatric disorders might be partially driven by sharable perinatal and neonatal environmental factors for mental disorders. Participants were 6–14 years of age children and their parents. Primary caregivers provided data on perinatal and neonatal information assessed retrospectively (n = 2231). Psychiatric disorders diagnoses were assessed using the Development and Well Being Behavior Assessment (DAWBA). We used bifactor models to disentangle common from dissociable aspects of psychopathology. These models allow modeling psychiatric disorders as the result of a common domain of psychopathology (p-factor) and three dissociable domains (fear, distress, and externalizing symptoms). Associations were tested using linear and tobit regression models. The p-factor was associated with male sex, low socioeconomic status, gestational smoking, gestational drinking, low levels of maternal education and presence of mental disorder in the mother. Associations with specific factors also emerged suggesting some risk factors might also have some role for fear, distress and externalizing factors. Our study supports the hypothesis that overall susceptibility to psychopathology might be partially driven by sharable perinatal and neonatal factors.

Item Type:	Article
Official URL:	https://link.springer.com/journal/787
Additional Information:	© 2024 The Author(s), under exclusive licence to Springer-Verlag GmbH Germany
Divisions:	LSE
Subjects:	R Medicine > RJ Pediatrics > RJ101 Child Health. Child health services B Philosophy. Psychology. Religion > BF Psychology
Date Deposited:	09 Apr 2024 13:12
Last Modified:	15 Apr 2024 09:27
URI:	http://eprints.lse.ac.uk/id/eprint/122586

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