The effectiveness of a primary care-based collaborative care model to improve quality of life in people with severe mental illness: PARTNERS2 cluster randomised controlled trial

Byng, Richard, Creanor, Siobhan, Jones, Benjamin, Hosking, Joanne, Plappert, Humera, Bevan, Sheriden, Britten, Nicky, Clark, Michael ORCID: 0000-0003-4964-5005, Davies, Linda, Frost, Julia, Gask, Linda, Gibbons, Bliss, Gibson, John, Hardy, Pollyanna, Hobson-Merrett, Charley, Huxley, Peter, Jeffery, Alison, Marwaha, Steven, Rawcliffe, Tim, Reilly, Siobhan, Richards, Debra, Sayers, Ruth, Williams, Lynsey, Pinfold, Vanessa and Birchwood, Maximillian (2023) The effectiveness of a primary care-based collaborative care model to improve quality of life in people with severe mental illness: PARTNERS2 cluster randomised controlled trial. The British journal of psychiatry : the journal of mental science, 222 (6). 246 - 256. ISSN 0007-1250

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Abstract

BACKGROUND: Individuals living with severe mental illness can have significant emotional, physical and social challenges. Collaborative care combines clinical and organisational components. AIMS: We tested whether a primary care-based collaborative care model (PARTNERS) would improve quality of life for people with diagnoses of schizophrenia, bipolar disorder or other psychoses, compared with usual care. METHOD: We conducted a general practice-based, cluster randomised controlled superiority trial. Practices were recruited from four English regions and allocated (1:1) to intervention or control. Individuals receiving limited input in secondary care or who were under primary care only were eligible. The 12-month PARTNERS intervention incorporated person-centred coaching support and liaison work. The primary outcome was quality of life as measured by the Manchester Short Assessment of Quality of Life (MANSA). RESULTS: We allocated 39 general practices, with 198 participants, to the PARTNERS intervention (20 practices, 116 participants) or control (19 practices, 82 participants). Primary outcome data were available for 99 (85.3%) intervention and 71 (86.6%) control participants. Mean change in overall MANSA score did not differ between the groups (intervention: 0.25, s.d. 0.73; control: 0.21, s.d. 0.86; estimated fully adjusted between-group difference 0.03, 95% CI -0.25 to 0.31; P = 0.819). Acute mental health episodes (safety outcome) included three crises in the intervention group and four in the control group. CONCLUSIONS: There was no evidence of a difference in quality of life, as measured with the MANSA, between those receiving the PARTNERS intervention and usual care. Shifting care to primary care was not associated with increased adverse outcomes.

Item Type:	Article
Official URL:	https://www.cambridge.org/core/journals/the-britis...
Additional Information:	© 2023 The Author(s)
Divisions:	Personal Social Services Research Unit
Subjects:	R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine
Date Deposited:	01 Jun 2023 09:24
Last Modified:	25 Apr 2024 18:36
URI:	http://eprints.lse.ac.uk/id/eprint/119294

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