Clare, Linda, Gamble, Laura D, Martyr, Anthony, Sabatini, Serena, Nelis, Sharon M, Quinn, Catherine, Pentecost, Claire, Victor, Christina, Jones, Roy W, Jones, Ian R, Knapp, Martin ORCID: 0000-0003-1427-0215, Litherland, Rachael, Morris, Robin G, Rusted, Jennifer M, Thom, Jeanette M, Collins, Rachel, Henderson, Catherine and Matthews, Fiona E
(2022)
Longitudinal trajectories of quality of life among people with mild-to-moderate dementia: a latent growth model approach with IDEAL cohort study data.
Journals of Gerontology - Series B Psychological Sciences and Social Sciences, 77 (6).
1037 - 1050.
ISSN 1079-5014
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Abstract
OBJECTIVES: We aimed to examine change over time in self-rated quality of life (QoL) in people with mild-to-moderate dementia and identify subgroups with distinct QoL trajectories. METHODS: We used data from people with mild-to-moderate dementia followed up at 12 and 24 months in the Improving the experience of Dementia and Enhancing Active Life (IDEAL) cohort study (baseline n = 1,537). A latent growth model approach examined mean change over time in QoL, assessed with the QoL-AD scale, and investigated associations of baseline demographic, cognitive, and psychological covariates with the intercept and slope of QoL. We employed growth mixture modeling to identify multiple growth trajectories. RESULTS: Overall mean QoL scores were stable and no associations with change over time were observed. Four classes of QoL trajectories were identified: 2 with higher baseline QoL scores, labeled Stable (74.9%) and Declining (7.6%), and 2 with lower baseline QoL scores, labeled Stable Lower (13.7%) and Improving (3.8%). The Declining class had higher baseline levels of depression and loneliness, and lower levels of self-esteem and optimism, than the Stable class. The Stable Lower class was characterized by disadvantage related to social structure, poor physical health, functional disability, and low psychological well-being. The Improving class was similar to the Stable Lower class but had lower cognitive test scores. DISCUSSION: Understanding individual trajectories can contribute to personalized care planning. Efforts to prevent decline in perceived QoL should primarily target psychological well-being. Efforts to improve QoL for those with poorer QoL should additionally address functional impairment, isolation, and disadvantage related to social structure.
Item Type: | Article |
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Official URL: | https://academic.oup.com/psychsocgerontology |
Additional Information: | © 2022 The Authors |
Divisions: | Personal Social Services Research Unit |
Subjects: | R Medicine > RA Public aspects of medicine |
Date Deposited: | 25 Mar 2022 10:12 |
Last Modified: | 10 Aug 2024 02:03 |
URI: | http://eprints.lse.ac.uk/id/eprint/114468 |
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