Library Header Image
LSE Research Online LSE Library Services

Treatment gaps in severe asthma across nine OECD countries and recommendations for addressing them: an international survey of clinicians

Efthymiadou, Olina, Kamphuis, Bregtje, Kanavos, Panos ORCID: 0000-0001-9518-3089 and Tzouma, Victoria (2021) Treatment gaps in severe asthma across nine OECD countries and recommendations for addressing them: an international survey of clinicians. . LSE Consulting, London, UK.

[img] Text (Severe asthma care and treatment_WP2_Final_May 2021) - Published Version
Download (1MB)


OBJECTIVES: Despite recent advancements in the pharmacological management of severe asthma (SA), there is a significant lack of robust, system level data on the diagnostic, prescribing and care practices in SA. This hinders performance measurement and improved quality in SA care outcomes. This paper aimed to capture clinician and patient insights on outcomes relevant to the clinical and pharmacological management of SA and understand the extent to which this evidence can facilitate performance and quality measurement efforts in SA care. METHODS: Following an in-depth review of the relevant literature, we developed a robust framework of SA relevant indicators around: a) policy structure and organisation; b) diagnosis; c) treatment; and d) care delivery. We conducted an international web survey of respiratory specialists to capture information on the above indicators and provide comparative insights and benchmarking of performance in SA across 9 countries. RESULTS: Twenty-six responses were received from respiratory specialists in Australia, Brazil, Canada, France, Germany, Italy, Japan, Spain, and UK. The insights revealed that SA-specific quality-of-care frameworks are largely unavailable across all study countries, while discrepancies existed across and within settings on practices and timings for specialist referral and appointment booking: the former ranging from 19 days in Germany and up to 24 months in Brazil. Variation was more prominent in the diagnostic criteria and tests used, with only about a third of surveyed clinicians reporting using SA diagnostic pathway guidelines. A disconnect both between and within countries exists in the prescribing pathways followed to treat and manage SA, especially in relation to the use of oral/systemic corticosteroids. CONCLUSION: Data around the clinical and pharmacological management of SA is not routinely available, and despite the increased use of biologics there are still significant gaps in patient care holding back improved outcomes. In light of the COVID-19 pandemic, action in the form of measures to enhance outcomes in SA care is vital now more than ever. These include measures for: i) the systematic collection of outcomes data in SA, ii) improved referral pathways and capacities in SA and iii) measures to support increased understanding and incentivisation of guidelines in the prescribing of treatment and SA diagnostic criteria.

Item Type: Monograph (Report)
Additional Information: © by Olina Efthymiadou MSc, Bregtje Kamphuis MSc, Panos Kanavos PhD, and Victoria Tzouma MSc.
Divisions: Health Policy
Date Deposited: 06 May 2021 11:06
Last Modified: 02 Aug 2021 23:05

Actions (login required)

View Item View Item


Downloads per month over past year

View more statistics