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Distress improves after mindfulness training for progressive MS: a pilot randomised trial

Bogosian, A., Chadwick, P., Windgassen, S., Norton, S., McCrone, P., Mosweu, Iris, Silber, E. and Moss-Morris, R. (2015) Distress improves after mindfulness training for progressive MS: a pilot randomised trial. Multiple Sclerosis Journal, 21 (9). 1184 - 1194. ISSN 1352-4585

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Identification Number: 10.1177/1352458515576261


Background: Mindfulness-based interventions have been shown to effectively reduce anxiety, depression and pain in patients with chronic physical illnesses. Objectives: We assessed the potential effectiveness and cost-effectiveness of a specially adapted Skype distant-delivered mindfulness intervention, designed to reduce distress for people affected by primary and secondary progressive MS. Methods: Forty participants were randomly assigned to the eight-week intervention (n = 19) or a waiting-list control group (n = 21). Participants completed standardised questionnaires to measure mood, impact of MS and symptom severity, quality of life and service costs at baseline, post-intervention and three-month follow-up. Results: Distress scores were lower in the intervention group compared with the control group at postintervention and follow-up (p < 0.05), effect size -0.67 post-intervention and -0.97 at follow-up. Mean scores for pain, fatigue, anxiety, depression and impact of MS were reduced for the mindfulness group compared with control group at post-therapy and follow-up; effect sizes ranged from -0.27 to -0.99 postintervention and -0.29 to -1.12 at follow-up. There were no differences in quality-adjusted life years, but an 87.4% probability that the intervention saves on service costs and improves outcome. Conclusions: A mindfulness intervention delivered through Skype video conferences appears accessible, feasible and potentially effective and cost-effective for people with progressive MS.

Item Type: Article
Official URL:
Additional Information: © 2015 The Authors
Divisions: Health Policy
Subjects: R Medicine > RA Public aspects of medicine
B Philosophy. Psychology. Religion > BF Psychology
Date Deposited: 02 Sep 2020 07:09
Last Modified: 20 Oct 2021 01:03

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