Cookies?
Library Header Image
LSE Research Online LSE Library Services

Dynamics of beneficial epidemics

Berdahl, Andrew, Brelsford, Christa, Bacco, Caterina De, Dumas, Marion, Ferdinand, Vanessa, Grochow, Joshua A., Hébert-Dufresne, Laurent, Kallus, Yoav, Kempes, Christopher P., Kolchinsky, Artemy, Larremore, Daniel B., Libby, Eric, Power, Eleanor A. ORCID: 0000-0002-3064-2050, Stern, Caitlin A. and Tracey, Brendan D. (2019) Dynamics of beneficial epidemics. Scientific Reports, 9 (1). ISSN 2045-2322

[img] Text (Dynamics of beneficial epidemics) - Published Version
Available under License Creative Commons Attribution.

Download (1MB)

Identification Number: 10.1038/s41598-019-50039-w

Abstract

Pathogens can spread epidemically through populations. Beneficial contagions, such as viruses that enhance host survival or technological innovations that improve quality of life, also have the potential to spread epidemically. How do the dynamics of beneficial biological and social epidemics differ from those of detrimental epidemics? We investigate this question using a breadth-first modeling approach involving three distinct theoretical models. First, in the context of population genetics, we show that a horizontally-transmissible element that increases fitness, such as viral DNA, spreads superexponentially through a population, more quickly than a beneficial mutation. Second, in the context of behavioral epidemiology, we show that infections that cause increased connectivity lead to superexponential fixation in the population. Third, in the context of dynamic social networks, we find that preferences for increased global infection accelerate spread and produce superexponential fixation, but preferences for local assortativity halt epidemics by disconnecting the infected from the susceptible. We conclude that the dynamics of beneficial biological and social epidemics are characterized by the rapid spread of beneficial elements, which is facilitated in biological systems by horizontal transmission and in social systems by active spreading behavior of infected individuals.

Item Type: Article
Official URL: https://www.nature.com/srep/
Additional Information: © 2019 The Authors
Divisions: Methodology
Subjects: R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine
Date Deposited: 31 Oct 2019 12:21
Last Modified: 14 Sep 2024 08:02
URI: http://eprints.lse.ac.uk/id/eprint/102307

Actions (login required)

View Item View Item

Downloads

Downloads per month over past year

View more statistics