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Using generic preference-based measures in mental health: psychometric validity of the EQ-5D and SF-6D

Mulhern, Brendan and Mukuria, Clara and Barkham, Michael and Knapp, Martin and Byford, S. and Soeteman, Djøra and Brazier, John (2014) Using generic preference-based measures in mental health: psychometric validity of the EQ-5D and SF-6D. British Journal of Psychiatry, 205 (3). pp. 236-243. ISSN 0007-1250

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Identification Number: 10.1192/bjp.bp.112.122283

Abstract

Background: Generic preference-based measures (EuroQoL-5D (EQ-5D) and SF-6D) are used in the economic evaluation of mental health interventions. However, there are inconsistent findings regarding their psychometric properties. Aims: To investigate the psychometric properties of the EQ-5D and SF-6D in different mental health conditions, using seven existing data-sets. Method: The construct validity and responsiveness of the measures were assessed in comparison with condition-specific indicators. Results: Evidence for construct validity and responsiveness in common mental health and personality disorders was found (correlations 0.22-0.64; effect sizes 0.37-1.24; standardised response means 0.45-1.31). There was some evidence for validity in schizophrenia (correlations 0.05-0.43), but responsiveness was unclear. Conclusions: EQ-5D and SF-6D can be used in the economic evaluation of interventions for common mental health problems with some confidence. In schizophrenia, a preference-based measure focused on the impact of mental health should be considered.

Item Type: Article
Official URL: http://bjp.rcpsych.org/
Subjects: R Medicine > RA Public aspects of medicine
Sets: Departments > Social Policy
Research centres and groups > Personal Social Services Research Unit (PSSRU)
Research centres and groups > NIHR School for Social Care Research
Date Deposited: 10 Oct 2014 11:34
Last Modified: 26 Oct 2017 14:30
URI: http://eprints.lse.ac.uk/id/eprint/59699

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