Library Header Image
LSE Research Online LSE Library Services

Issues in the incorporation of economic perspectives and evidence into Cochrane reviews

Campbell and Cochrane Economics Methods Group (2013) Issues in the incorporation of economic perspectives and evidence into Cochrane reviews. Systematic Reviews, 2 (83). ISSN 2046-4053

PDF - Published Version
Download (1MB) | Preview
Identification Number: 10.1186/2046-4053-2-83


Background: Methods for systematic reviews of the effects of health interventions have focused mainly on addressing the question of 'What works?' or 'Is this intervention effective in achieving one or more specific outcomes?' Addressing the question 'Is it worth it given the resources available?' has received less attention. This latter question can be addressed by applying an economic lens to the systematic review process. This paper reflects on the value and desire for the consideration by end users for coverage of an economic perspective in a Cochrane review and outlines two potential approaches and future directions. Methods: Two frameworks to guide review authors who are seeking to include an economic perspective are outlined. The first involves conducting a full systematic review of economic evaluations that is integrated into a review of intervention effects. The second involves developing a brief economic commentary. The two approaches share a set of common stages but allow the tailoring of the economic component of the Cochrane review to the skills and resources available to the review team. Results: The number of studies using the methods outlined in the paper is limited, and further examples are needed both to explore the value of these approaches and to further develop them. The rate of progress will hinge on the organisational leadership, capacity and resources available to the CCEMG, author teams and other Cochrane entities. Particular methodological challenges to overcome relate to understanding the key economic trade-offs and casual relationships for a given decision problem and informing the development of evaluations designed to support local decision-makers. Conclusions: Methods for incorporating economic perspectives and evidence into Cochrane intervention reviews are established. Their role is not to provide a precise estimate of 'cost-effectiveness' but rather to help end-users of Cochrane reviews to determine the implications of the economic components of reviews for their own specific decisions.

Item Type: Article
Official URL:
Additional Information: © 2013 The Authors ; licensee BioMed Central Ltd. © CC-BY 2.0
Divisions: Social Policy
Personal Social Services Research Unit
LSE Health
Subjects: H Social Sciences > H Social Sciences (General)
H Social Sciences > HC Economic History and Conditions
R Medicine > RA Public aspects of medicine
Date Deposited: 27 Sep 2013 08:15
Last Modified: 01 Jun 2024 03:11
Projects: Cochrane Methodology Anniversary Series
Funders: Erin Graybill

Actions (login required)

View Item View Item


Downloads per month over past year

View more statistics