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Relapse in schizophrenia: costs, clinical outcomes and quality of life

Almond, Stephen, Knapp, Martin ORCID: 0000-0003-1427-0215, Francois, Clement, Toumi, Mondher and Brugha, Traolach (2004) Relapse in schizophrenia: costs, clinical outcomes and quality of life. British Journal of Psychiatry, 184 (4). pp. 346-351. ISSN 0007-1250

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Identification Number: 10.1192/bjp.184.4.346


Background: Relapse is one of the most costly aspects of schizophrenia. Aims: To compare costs, clinical outcomes and quality of life for patients who experienced relapse in schizophrenia with a control group who did not relapse. Method: Patients were randomly selected from current psychiatric case-loads drawn from urban and suburban areas of Leicester. Differences in costs and outcomes by relapse status in the previous 6 months were examined using parametric and non-parametric tests, and multivariate analysis was used to examine factors associated with relapse and costs. Results: Costs for the patients who relapsed were over four times higher than those for the non-relapse group. There were few statistically significant differences in clinical and quality of life measures by relapse status. Multivariate analyses suggested some significant correlates of relapse and costs. Conclusions: The higher costs associated with relapse will be of interest to policy-makers who face difficultchoices concerning new but more expensive treatments for patients with schizophrenia.

Item Type: Article
Official URL:
Additional Information: © 2004 Royal College of Psychiatrists
Divisions: Social Policy
Personal Social Services Research Unit
LSE Health
Subjects: R Medicine > R Medicine (General)
H Social Sciences > HV Social pathology. Social and public welfare. Criminology
Date Deposited: 05 Sep 2008 14:21
Last Modified: 07 Dec 2021 16:18

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